Effect of Growth Hormone Replacement Therapy on Cognition after Traumatic Brain Injury
نویسندگان
چکیده
منابع مشابه
Catecholamines and cognition after traumatic brain injury
Cognitive problems are one of the main causes of ongoing disability after traumatic brain injury. The heterogeneity of the injuries sustained and the variability of the resulting cognitive deficits makes treating these problems difficult. Identifying the underlying pathology allows a targeted treatment approach aimed at cognitive enhancement. For example, damage to neuromodulatory neurotransmit...
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Introduction: Following a traumatic brain injury (TBI), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. This study examined the changes in brain concentrations of proinflammatory cytokines IL-1, IL-6, TNF-α and TGF- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post...
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OBJECTIVE The effects of growth hormone on cognitive dysfunction were observed in a controlled cortical impact (CCI) rat model and the underlying mechanism was explored. METHOD Three-month-old male SD rats were randomly divided into sham (n = 10), control (n = 10), and CCI groups (n = 40) The parameters were set as follows: striking speed, 3.5 m/s; impact depth, 1.5 mm; and dwell time, 400 ms...
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لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملICP/CPP therapy after traumatic brain injury
Objective: To evaluate the effects of a brain tissue oxygen (PtiO2) guided treatment in patients with traumatic brain injury. Methods: PtiO2 was monitored in 93 patients with severe traumatic brain injury. Forty patients admitted from 1993 to 1996 were treated with intracranial pressure/cerebral perfusion pressure (ICP/CPP) management alone (ICP < 20 mm Hg, CPP > 70 mm Hg). Fifty three patients...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2010
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2009.1253